Robert MacLaren DPhil FRCS FRCOphth
Research Themes
Divisional Themes
- Genetics and Genomics
NLO Themes
Group Members
- Dr Alun Barnard, Senior Postdoctoral Reseacher
- Mr Markus Groppe, NIHR Academic Clinical Lecturer
- Dr Michelle McClements, Fight for Sight Research Fellow
- Dr Peter Charbel Issa, Marie Curie Clinical Research Fellow
- Mr Daniel Lipinski, Fight for Sight PhD Student
- Dr Mandeep Singh, Research Fellow and Merton Prize Scholar
- Dr Haidong Shan, China Scholarship Council Student
- Major Sher Aslam RAMC, Ministry of Defence Research Fellow
- Dr Sam de Silva, Wellcome Trust Clinical Research Training Fellow
- Miss Alona Cramer, Clarendon Scholar and DPhil Student
- Miss Jaspreet Kangura, Rhodes Scholar and MSc Student
- Dr Rachel Butler, Laboratory Manager
Former Group Members
- Dr Qisheng You, Vitreoretinal Surgeon, Tongren Eye Hospital, Beijing, China
- Dr Thanos Vachtsevanos, Trainee Ophthalmologist, Thessaloniki, Greece
- Dr Georgia Perganta, Trainee Ophthalmologist, Thessaloniki, Greece
- Dr Nathan Walker, Vitreoretinal Surgeon, Brisbane, Australia
Recent Publications
- Lee E and MacLaren R E (2011) Sources of retinal pigment epithelium (RPE) for replacement therapy. Br J Ophthalmol, 95(4):445-9.
- Smith Henry B, Sabrosa Nelson A, Patton Niall, and MacLaren Robert E (2011) Combined phacoemulsification and removal of gas following macular hole surgery. J Cataract Refract Surg, 37(2):229-34.
- Comyn Oliver, Lee Edward, and MacLaren Robert E (2010) Induced pluripotent stem cell therapies for retinal disease. Curr Opin Neurol, 23(1):4-9.
- Pearson RA, Barber AC, West EL, MacLaren RE, Duran Y, Bainbridge JW, Sowden JC, and Ali RR (2010) Targeted disruption of outer limiting membrane junctional proteins (Crb1 and ZO-1) increases integration of transplanted photoreceptor precursors into the adult wild-type and degenerating retina. Cell Transplant, 19(4):487-503.
- Sohn EH, Chen FK, Rubin GS, Moore AT, Webster AR, and MacLaren RE (2010) Macular function assessed by microperimetry in patients with enhanced S-cone syndrome Ophthalmology, 117(6):1199-1206.
| Contact address | Levels 5 & 6 West Wing, The John Radcliffe Hospital, Headley Way, Oxford, Oxfordshire, OX3 9DU, United Kingdom |
|---|---|
| Department | Department of Ophthalmology |
| College | Merton College |
Robert MacLaren
Our clinical and laboratory research is dedicated to finding new treatments for blindness, particularly in patients with incurable retinal diseases. In addition to developing gene therapy with new adeno-associated viral (AAV) vectors in the laboratory, we are currently leading a gene therapy trial to treat choroideraemia. We are also developing treatments for other macular and retinal degenerations. We have a clinical research program in artifical vision with bio-genetic and electronic devices. In the clinic we are testing new imaging methods for retinal diseases and in the operating theatre we are developing new eye surgery techniques for age-related macular degeneration, cataract and macular hole surgery.
Sources of Funding
- The Health Foundation
- The Medical Research Council UK
- The Royal Blind
- The Scottish National Institute for the War Blinded
- The Royal College of Surgeons of Edinburgh
- The Special Trustees of Moorfields Eye Hospital
- The Wellcome Trust
- Fight for Sight
- The Lanvern Foundation
- The Oxford Stem Cell Institute
- The National Institute for Health Research
Biography
Robert MacLaren is Professor of Ophthalmology at the University of Oxford, Consultant Ophthalmologist at the Oxford Eye Hospital, Honorary Professor of Ophthalmology at the UCL Institute of Ophthalmology, Honorary Consultant Vitreoretinal Surgeon at Moorfields Eye Hospital, Honorary Consultant Ophthalmologist at Great Ormond Street Children's Hospital, Faculty Member and Founding Theme Leader of the Moorfields-UCL Institute of Ophthalmology Biomedical Research Centre. He is also a Fellow of the Royal College of Ophthalmologists, Fellow and former King James IV Professor of Surgery at the Royal College of Surgeons of Edinbugh, Fellow of the Higher Education Academy and Bodley Fellow of Merton College Oxford.
Images
